Shanghai (China), Daejeon (South Korea)，January 5th 2021 - 3D Medicines Inc., a clinical stage biopharmaceutical company focusing on the development and commercialization of differentiated immuno-oncology drugs, and Y-Biologics, the South Korean biotech company, have entered into a license agreement, and 3D Medicines will obtain exclusive rights to develop, manufacture, and commercialize YBL-013, a T cell bi-specific engager based on ALiCE platform technology, in the Territory of Greater China (mainland China, Hong Kong, Macau and Taiwan) and will co-developed it across the globe. For 3D Medicines, acquiring this candidate drug will further improve its product layout in the field of immune-oncology, and build a highly competitive and complementary pipeline.

December 22, 2020 - 3D Medicines Inc. announced the New Drug Application (NDA) of Envafolimab (KN035), a recombinant humanized PD-L1 single-domain antibody has been accepted by the National Medical Products Administration (NMPA) on December 17, with the registration number CXSS2000060 for the indications of previously treated microsatellite instability-high (MSI-H)/deficient mismatch repair (dMMR) advanced colorectal cancer, gastric cancer and other advanced solid tumors. 3D Medicines, Alphamab Biopharmaceuticals Co., Ltd. (9966.HK) and Simcere Pharmaceutical Group Ltd. (2096.HK) reached the strategic collaboration on Envafolimab (KN035), the PD-L1 inhibitor formulated for subcutaneous injection, which can fill the unmet clinical needs after the marketing approval.

SHANGHAI and NEW YORK, December 8, 2020 -- 3D Medicines, Inc., a clinical stage biopharmaceutical company focusing on the development and commercialization of differentiated immuno-oncology drugs, and SELLAS Life Sciences Group, Inc. (Nasdaq: SLS) (“SELLAS”), a late-stage clinical biopharmaceutical company focusing on the development of novel cancer immunotherapies for a broad range of cancer indications, today announced that they have entered into an Exclusive License Agreement granting rights to 3D Medicines to develop and commercialize SELLAS’ lead clinical candidate, galinpepimut-S (GPS) and candidate GPS+ at preclinical stage, across all therapeutic and diagnosis uses in the Greater China territory (mainland China, Hong Kong, Macau and Taiwan). 

November 16, 2020, 3D Medicines Inc. announced the New Drug Application (NDA) of Envafolimab (KN035), a recombinant humanized PD-L1 single-domain antibody, which has reached the strategic collaboration with Alphamab Biopharmaceuticals Co., Ltd. (9966.HK) and Simcere Pharmaceutical Group Ltd. (2096.HK). The application has been officially submitted to the National Medical Products Administration (NMPA), and the indications are for the treatment of microsatellite instability (MSI-H) in advanced colorectal cancer, gastric cancer, and other mismatch repair defective (dMMR) advanced solid cancers that have failed previous standard treatment.

Shanghai, November 11, 2020, and Houston, TX, United States, November 10, 2020 – 3D Medicines, Inc., a biopharmaceutical company focusing on the R&D and commercialization of innovative immuno-oncology drugs, and Aravive, Inc. (Nasdaq: ARAV), a new biopharmaceutical company, today announced an exclusive collaboration and license agreement for the development and commercialization of AVB-500 in mainland China, Hong Kong, Macau, and Taiwan (Greater China).

Shanghai, October 27, 2020 - 3D Medicines, Inc. (3D Medicines) and Shanghai Haihe Pharmaceutical Co.,Ltd (Haihe Biopharma) today announced a collaboration agreement on Haihe Biopharma‘s innovative analgesics of RMX1001 and RMX1002. 3D Medicines will obtain the exclusive authorization for R&D, production and commercialization of RMX1001 and RMX1002 in China，which was an important move for 3D Medicines to envision a future when cancer is managed as a chronic disease, helping to further form a highly complementary pipeline of 3D Medicines.